Biomimetic hydroxyapatite and caries prevention: a systematic review and meta-analysis.

ABSTRACT: Dental caries is still one of the most prevalent diseases worldwide. Research has shown that fluoride has a role in caries prevention. For many reasons there are concerns about young children using fluoride-containing oral care products. Consequently, there is a need to identify effective fluoride-free products. A large body of literature now exists on the use of biomimetic hydroxyapatite (HAP) as an active ingredient in oral care products to combat caries.

Aim

To conduct a systematic review of the clinical evidence of the effects of HAP-based fluoride-free oral care products in caries reduction and conduct a meta-analysis of available randomized clinical trials (RCTs).

Methods

Using the PICO question "In individuals of all ages (P), do fluoride-free oral care products contai

SUBMITTER: Limeback H 

PROVIDER: S-EPMC8641555 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature