The extent to which off-patent registered prescription medicines are used for off-label indications in Australia: A scoping review.

ABSTRACT:

Aim

The aim of this scoping review was to determine the extent of off-patent prescription medicine use beyond registered indications in various Australian clinical settings.

Method

The review followed the Joanna Briggs Institute approach and reported using PRISMA Extension for Scoping Reviews. Online databases were used to identify published literature about off-patent registered prescription medicines used for off-label indications in Australian public hospital, community and primary healthcare settings. In addition, empirical data from the Queensland and the South Australian state-wide medicine formularies were screened for the same medication/off-label indication dyads identified in the literature, and other locally approved uses.

Results

Overall, fourteen studies

SUBMITTER: Howe K 

PROVIDER: S-EPMC8641869 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature