Statin Therapy in Patients Undergoing Thoracic Aorta Replacement for Aortic Aneurysms.

ABSTRACT:

Background

 Patients undergoing surgery for thoracic aortic aneurysms receive statin therapy out of proportion to cardiovascular comorbidity. We sought to determine the prevalence of statin use among patients presenting for thoracic aortic aneurysm surgery and investigate its effect on outcomes.

Methods

 From January 1, 2005 to January 1, 2011, 1,839 consecutive patients underwent aortic replacement for degenerative thoracic aortic aneurysm at Cleveland Clinic. Of these, 771 (42%) were on statins preoperatively. Statin users (vs. nonstatin users) were older (65 ± 11 vs. 56 ± 16 years) and had more hypertension (78 vs. 59%). Propensity matching based on 56 preoperative variables other than lipid levels was used to compare outcomes among 570 matched patient pairs (74% of possi

SUBMITTER: Kindzelski BA 

PROVIDER: S-EPMC8642073 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature