Predicted Vitamin D Status and Colorectal Cancer Incidence in the Black Women's Health Study.

ABSTRACT:

Background

Observational studies, mostly among White populations, suggest that low vitamin D levels increase colorectal cancer risk. African Americans, who are disproportionately burdened by colorectal cancer, often have lower vitamin D levels compared with other populations.

Methods

We assessed predicted vitamin D score in relation to colorectal cancer among 49,534 participants in the Black Women's Health Study, a cohort of African American women followed from 1995 to 2017 through biennial questionnaires. We derived predicted vitamin D scores at each questionnaire cycle for all participants using a previously validated prediction model based on actual 25-hydroxyvitamin D values from a subset of participants. We calculated cumulative average predicted vitamin D score at ever

SUBMITTER: Barber LE 

PROVIDER: S-EPMC8643345 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature