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Hot Topics in Recent Parkinson's Disease Research: Where We are and Where We Should Go.

ABSTRACT: Parkinson's disease (PD), the second most common neurodegenerative disease, is clinically characterized by both motor and non-motor symptoms. Although overall great achievements have been made in elucidating the etiology and pathogenesis of PD, the exact mechanisms of this complicated systemic disease are still far from being clearly understood. Consequently, most of the currently-used diagnostic tools and therapeutic options for PD are symptomatic. In this perspective review, we highlight the hot topics in recent PD research for both clinicians and researchers. Some of these hot topics, such as sleep disorders and gut symptoms, have been neglected but are currently emphasized due to their close association with PD. Following these research directions in future PD research may help understand the nature of the disease and facilitate the discovery of new strategies for the diagnosis and therapy of PD.

SUBMITTER: Li S

PROVIDER: S-EPMC8643373 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Hot Topics in Recent Parkinson's Disease Research: Where We are and Where We Should Go.

Li Song S Jia Congcong C Li Tianbai T Le Weidong W

Neuroscience bulletin 20210727 12

Parkinson's disease (PD), the second most common neurodegenerative disease, is clinically characterized by both motor and non-motor symptoms. Although overall great achievements have been made in elucidating the etiology and pathogenesis of PD, the exact mechanisms of this complicated systemic disease are still far from being clearly understood. Consequently, most of the currently-used diagnostic tools and therapeutic options for PD are symptomatic. In this perspective review, we highlight the h ...[more]

PMID: 34313916

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Project description:ObjectiveMany publications on telerehabilitation for hip or knee arthroplasty have been published in recent years. However, no specific studies have attempted to characterize research hotspots, global research collaborations, or trends related to telerehabilitation after hip or knee arthroplasty. Therefore, the aim of this bibliometric analysis was to provide an overview of the current status of research and map the research landscape on telerehabilitation for joint replacement to understand current trends, identify research gaps, and guide future research directions.MethodsThe Web of Science Core Collection and PubMed were comprehensively searched to identify all relevant English-language documents published from 2003 to June 7, 2024. Data from these published studies were then cleaned and structured. CiteSpace and VOSviewer were used to conduct the bibliometric visualization and comparative analysis of countries, institutions, journals, authors, references, and keywords. Then, the map illustrating the research hotspots and knowledge structure was plotted based on the analysis results.ResultsA total of 229 records were obtained, and the number of articles published has increased steadily over the investigated period. The largest increase was observed in 2022. With the highest number of publications and centrality, the United States was the most influential country. The University of Sherbrooke was the most productive institution. Author Boissy P. ranked first in terms of the number of publications, while Tousignant M. ranked highest in cited authors, with 7 publications and 65 citations. The Journal of Arthroplasty published the greatest number of articles, with 29 publications. The most popular keywords from 2018 to 2023 were "home telerehabilitation," "older adults," and "physical therapy". In terms of the strongest citation burst, the top five keywords were associated with "total knee arthroplasty," "in home tele rehabilitation," "physical activity," "motion," and "range." The frontier keywords were "patient satisfaction," "mobile application," "self-efficacy," "fear avoidance model," "home assessment tool," and "cost benefit analysis."ConclusionsThe current status and trends in telerehabilitation for hip or knee arthroplasty are presented. A major concern at present is physical therapy for home telerehabilitation in the elderly. In the future, mobile app-based telerehabilitation programs for arthroplasty will continue to be encouraged, and some outcomes, such as "patient satisfaction," "self-efficacy," and "cost benefit analysis," are expected to receive more attention. Our work will serve as a valuable resource, providing fundamental references and a directional guide for future research.

Dataset Information

Hot Topics in Recent Parkinson's Disease Research: Where We are and Where We Should Go.

Publications

Hot Topics in Recent Parkinson's Disease Research: Where We are and Where We Should Go.

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