Bone remodelling patterns around orthodontic mini-implants migrating in bone: an experimental study in rat vertebrae.

ABSTRACT:

Background

Orthodontic implant migration has been clinically observed in presence of continuous loading forces. Recent studies indicate that osteocytes play a crucial role in this phenomenon.

Objectives

Aim of this study was to investigate local osteocytic gene expression, protein expression, and bone micro-structure in peri-implant regions of pressure and tension.

Material and methods

The present work reports a complementary analysis to a previous micro-computed tomography study. Two customized mini-implants were placed in one caudal rat vertebra and connected by a nickel-titanium contraction spring generating different forces (i.e. 0, 0.5, 1.0, and 1.5 N). Either at 2 or 8 weeks, the vertebrae were harvested and utilized for 1. osteocytic gene expression using laser

SUBMITTER: Becker K 

PROVIDER: S-EPMC8643410 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature