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BMI in childhood and adolescence is associated with impaired reproductive function-a population-based cohort study from birth to age 50 years.


ABSTRACT:

SUBMITTER: Laru J 

PROVIDER: S-EPMC8643422 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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BMI in childhood and adolescence is associated with impaired reproductive function-a population-based cohort study from birth to age 50 years.

Laru J J   Nedelec R R   Koivuaho E E   Ojaniemi M M   Järvelin M-R MR   Tapanainen J S JS   Franks S S   Tolvanen M M   Piltonen T T TT   Sebert S S   Morin-Papunen L L  

Human reproduction (Oxford, England) 20211001 11


<h4>Study question</h4>What is the association between childhood and adolescent BMI and reproductive capacity in women?<h4>Summary answer</h4>Adolescent girls with obesity had an increased risk of infertility and childlessness in adulthood independently of their marital status or the presence of polycystic ovary syndrome (PCOS).<h4>What is known already</h4>Girls with obesity (BMI (kg/m2)>95th percentile) more often exhibit menstrual irregularities and infertility problems as compared to those w  ...[more]

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