Proposed Anti-Inflammatory Diet Reduces Inflammation in Compliant, Weight-Stable Patients with Rheumatoid Arthritis in a Randomized Controlled Crossover Trial.

ABSTRACT:

Background

It is unclear to what extent adjuvant dietary intervention can influence inflammation in rheumatoid arthritis (RA).

Objectives

The objective was to assess the effects of dietary manipulation on inflammation in patients with RA.

Methods

In a crossover design, participants [n = 50, 78% females, median BMI (in kg/m2) 27, median age 63 y] were randomly assigned to begin with either a 10-wk portfolio diet of proposed anti-inflammatory foods (i.e., a high intake of fatty fish, whole grains, fruits, nuts, and berries) or a control diet resembling a Western diet with a 4-mo washout in between. This report evaluates the secondary outcome markers of inflammation among participants with stable medication. Analyses were performed using a linear mixed ANCOVA model.

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SUBMITTER: Hulander E 

PROVIDER: S-EPMC8643575 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature