Chlamydomonas proteases: classification, phylogeny, and molecular mechanisms.

ABSTRACT: Proteases can regulate myriad biochemical pathways by digesting or processing target proteins. While up to 3% of eukaryotic genes encode proteases, only a tiny fraction of proteases are mechanistically understood. Furthermore, most of the current knowledge about proteases is derived from studies of a few model organisms, including Arabidopsis thaliana in the case of plants. Proteases in other plant model systems are largely unexplored territory, limiting our mechanistic comprehension of post-translational regulation in plants and hampering integrated understanding of how proteolysis evolved. We argue that the unicellular green alga Chlamydomonas reinhardtii has a number of technical and biological advantages for systematic studies of proteases, including reduced complexity of many protease

SUBMITTER: Zou Y 

PROVIDER: S-EPMC8643629 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature