Use of Salivary Iodine Concentrations to Estimate the Iodine Status of Adults in Clinical Practice.

ABSTRACT:

Background

Measurement of the 24-h urinary iodine concentration or urinary iodine excretion (UIE) is the gold standard to determine iodine status; however, this method is inconvenient. The use of salivary iodine could be a possible alternative since salivary glands express the sodium-iodine symporter.

Objectives

We aimed to establish the correlation between the salivary iodine secretion and UIE, to evaluate the clinical applicability of the iodine saliva measurement.

Methods

We collected 24-h urine and saliva samples from 40 participants ≥18 y: 20 healthy volunteers with no specific diet (group 1), 10 patients with differentiated thyroid cancer with a low dietary intake (<50 μg/d, group 2), and 10 patients with a high iodine status as the result of the use of amiodaro

SUBMITTER: Dekker BL 

PROVIDER: S-EPMC8643657 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature