Exploring genetic diversity, population structure, and phylogeography in <i>Paracoccidioides</i> species using AFLP markers.

ABSTRACT: Paracoccidioidomycosis (PCM) is a life-threatening systemic fungal infection acquired after inhalation of Paracoccidioides propagules from the environment. The main agents include members of the P. brasiliensis complex (phylogenetically-defined species S1, PS2, PS3, and PS4) and P. lutzii. DNA-sequencing of protein-coding loci (e.g., GP43, ARF, and TUB1) is the reference method for recognizing Paracoccidioides species due to a lack of robust phenotypic markers. Thus, developing new molecular markers that are informative and cost-effective is key to providing quality information to explore genetic diversity within Paracoccidioides. We report using new amplified fragment length polymorphism (AFLP) markers and mating-type analysis for ge

SUBMITTER: Roberto TN 

PROVIDER: S-EPMC8645518 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature