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ABSTRACT: Background
This study aims to capture the 3D shape of the human skull in a healthy paediatric population (0-4 years old) and construct a generative statistical shape model.Methods
The skull bones of 178 healthy children (55% male, 20.8 ± 12.9 months) were reconstructed from computed tomography (CT) images. 29 anatomical landmarks were placed on the 3D skull reconstructions. Rotation, translation and size were removed, and all skull meshes were placed in dense correspondence using a dimensionless skull mesh template and a non-rigid iterative closest point algorithm. A 3D morphable model (3DMM) was created using principal component analysis, and intrinsically and geometrically validated with anthropometric measurements. Synthetic skull instances were generated exploiting the
SUBMITTER: O' Sullivan E
PROVIDER: S-EPMC8645852 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature