Ethnic differences and heritability of blood pressure circadian rhythm in African and European American youth and young adults.

ABSTRACT:

Background

The aim of this study was to investigate whether blood pressure (BP) circadian rhythm in African Americans differed from that in European Americans. We further examined the genetic and/or environmental sources of variances of the BP circadian rhythm parameters and the extent to which they depend on ethnicity or sex.

Method

Quantification of BP circadian rhythm was obtained using Fourier transformation from the ambulatory BP monitoring data of 760 individuals (mean age, 17.2 ± 3.3; 322 twin pairs and 116 singletons; 351 African Americans).

Results

BP circadian rhythm showed a clear difference by ethnic group with African Americans having a lower amplitude (P = 1.5e-08), a lower percentage rhythm (P = 2.8e-11), a higher MESOR (P = 2.5e-05) and being more like

SUBMITTER: Xu Y 

PROVIDER: S-EPMC8646444 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature