Ultrasensitive Detection of Dopamine, IL-6 and SARS-CoV-2 Proteins on Crumpled Graphene FET Biosensor.

ABSTRACT: Universal platforms for biomolecular analysis using label-free sensing modalities can address important diagnostic challenges. Electrical field effect-sensors are an important class of devices that can enable point-of-care sensing by probing the charge in the biological entities. Use of crumpled graphene for this application is especially promising. It is previously reported that the limit of detection (LoD) on electrical field effect-based sensors using DNA molecules on the crumpled graphene FET (field-effect transistor) platform. Here, the crumpled graphene FET-based biosensing of important biomarkers including small molecules and proteins is reported. The performance of devices is systematically evaluated and optimized by studying the effect of the crumpling ratio on electrical double l

SUBMITTER: Hwang MT 

PROVIDER: S-EPMC8646936 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature