Cardiac Troponin Is Elevated in Patients with Thyrotoxicosis and Decreases as Thyroid Function Improves and Brain Natriuretic Peptide Levels Decrease.

ABSTRACT:

Introduction

High-sensitive cardiac troponin reflects micro-myocardial injury in the absence of overt myocardial infarction.

Objective

This study aimed to clarify how thyrotoxicosis affects cardiac troponin.

Methods

This was a prospective observational study in Japan. Untreated patients with thyrotoxicosis who visited Ito Hospital were enrolled, and medical treatment was initiated for hyperthyroidism. Thyroid function, high-sensitive troponin I (hsTnI), and brain natriuretic peptide (BNP) were measured at baseline and then every 3 months for 1 year.

Results

Data from a total of 143 patients (median age, 42 years; 32 men and 111 women) were investigated. At baseline, median hsTnI was 1.9 pg/mL and ranged from 0 to 69.6 pg/mL. Five patients (3.5%) had a high hsTn

SUBMITTER: Watanabe N 

PROVIDER: S-EPMC8647084 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature