Redefining Tumor Burden in Patients with Intermediate-Stage Hepatocellular Carcinoma: The Seven-Eleven Criteria.

ABSTRACT:

Background and aims

For patients with intermediate-stage hepatocellular carcinoma (HCC), the definition of high tumor burden remains controversial. This study aimed to compare the prognostic value of different criteria of tumor burden in patients with intermediate-stage HCC undergoing transarterial chemoembolization (TACE).

Methods

From 2007 to 2019, 632 treatment-naive patients with intermediate-stage HCC undergoing TACE were retrospectively enrolled. We compared different criteria of tumor burden in discriminating radiologic response and survival, including up-to-7, up-to-11, 5-7, 7 lesions criteria, and newly proposed 7-11 criteria.

Results

The proportions of patients classified as high tumor burden were varied by different criteria. Among the 5 criteria, 7-11 crit

SUBMITTER: Hung YW 

PROVIDER: S-EPMC8647089 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature