Discordance between the triglyceride glucose index and HOMA-IR in incident albuminuria: a cohort study from China.

ABSTRACT:

Background

To date, there have no study comparing the associations between TyG index and HOMA-IR on the risk of incident albuminuria. Accordingly, the objective of the present study is to use discordance analysis to evaluate the diverse associations between TyG index and HOMA-IR on the risk of incident albuminuria.

Methods

A community-based prospective cohort study was performed with 2446 Chinese adults. We categorized participants into 4 concordance or discordance groups. Discordance was defined as a TyG index equal to or greater than the upper quartile and HOMA-IR less than the upper quartile, or vice versa.

Results

During a median follow-up period of 3.9 years, 203 of 2446 participants developed incident albuminuria (8.3%). In the multivariable logistic analyses, t

SUBMITTER: Gao W 

PROVIDER: S-EPMC8647334 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature