Ischaemic heart and cerebrovascular disease mortality in uranium enrichment workers.

ABSTRACT:

Objective

Linear and non-linear dose-response relationships between radiation absorbed dose to the lung from internally deposited uranium and external sources and circulatory system disease (CSD) mortality were examined in a cohort of 23 731 male and 5552 female US uranium enrichment workers.

Methods

Rate ratios (RRs) for categories of lung dose and linear excess relative rates (ERRs) per unit lung dose were estimated to evaluate the associations between lung absorbed dose and death from ischaemic heart disease (IHD) and cerebrovascular disease.

Results

There was a suggestion of modestly increased IHD risk in workers with internal uranium lung dose above 1 milligray (mGy) (RR=1.4, 95% CI 0.76 to 2.3) and a statistically significantly increased IHD risk with external d

SUBMITTER: Anderson JL 

PROVIDER: S-EPMC8647719 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature