Hemodynamic Predictors of Renal Function After Pediatric Left Ventricular Assist Device Implantation.

ABSTRACT: Although renal function often improves after pediatric left ventricular assist device (LVAD) implantation, recovery is inconsistent. We aimed to identify hemodynamic parameters associated with improved renal function after pediatric LVAD placement. A single-center retrospective cohort study was conducted in patients less than 21 years who underwent LVAD placement between June 2004 and December 2015. The relationship between hemodynamic parameters and estimated glomerular filtration rate (eGFR) was assessed using univariate and multivariate modeling. Among 54 patients, higher preoperative central venous pressure (CVP) was associated with eGFR improvement after implantation (p = 0.012). However, 48 hours postimplantation, an increase in CVP from baseline was associated with eGFR decline over

SUBMITTER: Chen CY 

PROVIDER: S-EPMC8647769 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature