Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species.

ABSTRACT: Polyploidization events are observed across the tree of life and occur in many fungi, plant, and animal species. During evolution, polyploidy is thought to be an important source of speciation and tumorigenesis. However, the origin of polyploid populations is not always clear, and little is known about the precise nature and structure of their complex genome. Using a long-read sequencing strategy, we sequenced 71 strains from the Brettanomyces bruxellensis yeast species, which is found in anthropized environments (e.g., beer, contaminant of wine, kombucha, and ethanol production) and characterized by several polyploid subpopulations. To reconstruct the polyploid genomes, we phased them by using different strategies and found that each subpopulation had a unique polyploidization hist

SUBMITTER: Eberlein C 

PROVIDER: S-EPMC8647821 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature