Evaluation of a Novel Absorbable Mesh in a Porcine Model of Abdominal Wall Repair.

ABSTRACT: Bioabsorbable meshes have seen increasing clinical use to reinforce soft tissue, and exist on a spectrum of strength loss versus absorption: several retain their strength for months, but remain in situ for years. Others lose strength fully by 6 weeks. An intermediate profile, with some strength for 3 -4 months, but consistent absorption in less than a year, may be an optimal balance of near-term support and long-term safety. In this large animal study, we evaluate such a mesh (DuraSorb, SIA), assessing its utility in a porcine model of abdominal wall repair.

Methods

Two full-thickness defects were created in the abdominal walls of nine Yucatan swine via midline approach and repaired preperitoneally with either DuraSorb or long-lasting control mesh (TIGR, Novus Scientific). At 30 day

SUBMITTER: Mlodinow AS 

PROVIDER: S-EPMC8647887 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature