Hybrid dedicated and distributed coding in PMd/M1 provides separation and interaction of bilateral arm signals.

ABSTRACT: Pronounced activity is observed in both hemispheres of the motor cortex during preparation and execution of unimanual movements. The organizational principles of bi-hemispheric signals and the functions they serve throughout motor planning remain unclear. Using an instructed-delay reaching task in monkeys, we identified two components in population responses spanning PMd and M1. A "dedicated" component, which segregated activity at the level of individual units, emerged in PMd during preparation. It was most prominent following movement when M1 became strongly engaged, and principally involved the contralateral hemisphere. In contrast to recent reports, these dedicated signals solely accounted for divergence of arm-specific neural subspaces. The other "distributed" component mixed signals

SUBMITTER: Dixon TC 

PROVIDER: S-EPMC8648118 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature