Relationship between sensory characteristics and cortical thickness/volume in autism spectrum disorders.

ABSTRACT: Individuals with autism spectrum disorders (ASDs) exhibit atypical sensory characteristics, impaired social skills, deficits in verbal and nonverbal communication, and restricted and repetitive behaviors. The relationship between sensory characteristics and brain morphological changes in ASD remains unclear. In this study, we investigated the association between brain morphological changes and sensory characteristics in individuals with ASD using brain image analysis and a sensory profile test. Forty-three adults with ASD and 84 adults with typical development underwent brain image analysis using FreeSurfer. The brain cortex was divided into 64 regions, and the cortical thickness and volume of the limbic system were calculated. The sensory characteristics of the participants were evaluated

SUBMITTER: Habata K 

PROVIDER: S-EPMC8648722 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature