The combined effects of age and HIV on the anatomic distribution of cortical and cancellous bone in the femoral neck among men and women.

ABSTRACT:

Objective

To investigate HIV-related and age-related differences in hip bone structure in men and women.

Design

Cross sectional study of bone structure and HIV serostatus.

Methods

We used Quantitative Computed Tomography (QCT) data from the Multicenter AIDS Cohort Study (MACS) and Women's Interagency HIV Study (WIHS) to examine cortical thickness (CT) and cortical (CBMD), trabecular (TBMD), and integral (IBMD) bone mineral density across anatomic quadrants of the femoral neck in older adult MSM and women with (PWH) and without (PWOH) HIV infection. The percentage difference (%diff) in the means for CT and BMD overall and by quadrant between PWH and PWOH were estimated.

Results

Among 322 MSM (median age 60 years) with bone measures, distributions were similar be

SUBMITTER: Abraham AG 

PROVIDER: S-EPMC8649032 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature