Edge-enhancing gradient echo with multi-image co-registration and averaging (EDGE-MICRA) for targeting thalamic centromedian and parafascicular nuclei.

ABSTRACT:

Background and purpose

Deep brain stimulation of the thalamus is an effective treatment for multiple neurological disorders. The centromedian and parafascicular nuclei are recently emerging targets for multiple conditions, such as epilepsy and Tourette syndrome; however, their limited visibility on conventional magnetic resonance imaging sequences has been a major obstacle. The goal of this study was to demonstrate the feasibility of a high-resolution and high-contrast targeting sequence for centromedian-parafascicular deep brain stimulation using a recently described magnetic resonance imaging sequence, three-dimensional edge-enhancing gradient echo.

Methods

The three-dimensional edge-enhancing gradient echo sequence was performed on a normal volunteer for a total of six ac

SUBMITTER: Middlebrooks EH 

PROVIDER: S-EPMC8649196 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature