Photophysical, photostability, and ROS generation properties of new trifluoromethylated quinoline-phenol Schiff bases.

ABSTRACT: A new series of ten examples of Schiff bases, namely (E)-2-(((2-alkyl(aryl/heteroaryl)-4-(trifluoromethyl)quinolin-6-yl)imino)methyl)phenols 3, was easily synthesized with yields of up to 91% from the reactions involving a series of 2-(R-substituted) 6-amino-4-(trifluoromethyl)quinolines 1 and 4(5)-R¹-substituted salicylaldehydes 2 - in which alkyl/aryl/heteroaryl for 2-R-substituents are Me, Ph, 4-MeC₆H₄, 4-FC₆H₄, 4-NO₂C₆H₄, and 2-furyl, and R¹-substituents are 5-NEt₂, 5-OCH₃, 4-Br, and 4-NO₂. Complementarily, the Schiff bases showed low to good quantum fluorescence yield values in CHCl₃ (Φ_f = 0.12-0.80), DMSO

SUBMITTER: Rocha IO 

PROVIDER: S-EPMC8649202 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature