Dataset Information

Vaccinating adolescents against SARS-CoV-2 in England: a risk-benefit analysis.

ABSTRACT:

Objective

To offer a quantitative risk-benefit analysis of two doses of SARS-CoV-2 vaccination among adolescents in England.

Setting

England.

Design

Following the risk-benefit analysis methodology carried out by the US Centers for Disease Control, we calculated historical rates of hospital admission, Intensive Care Unit admission and death for ascertained SARS-CoV-2 cases in children aged 12-17 in England. We then used these rates alongside a range of estimates for incidence of long COVID, vaccine efficacy and vaccine-induced myocarditis, to estimate hospital and Intensive Care Unit admissions, deaths and cases of long COVID over a period of 16 weeks under assumptions of high and low case incidence.