Predictors of Carotid Intima-Media Thickness Progression in Adolescents-The EVA-Tyrol Study.

ABSTRACT: Background Cardiovascular disease depends on the duration and time course of risk factor exposure. Previous reports on risk factors of progression of carotid intima-media thickness (cIMT) in the young were mostly restricted to high-risk populations or susceptible to certain types of bias. We aimed to unravel a risk factor signature for early vessel pathology based on repeated ultrasound assessments of the carotid arteries in the general population. Methods and Results Risk factors were assessed in 956 adolescents sampled from the general population with a mean age of 15.8±0.9 years, 56.2% of whom were female. cIMT was measured at baseline and on average 22.5±3.4 months later by high-resolution ultrasound. Effects of baseline risk factors on cIMT progression were investigated using linear m

SUBMITTER: Kiechl SJ 

PROVIDER: S-EPMC8649517 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature