Efficacy and safety of glucocorticoids in the treatment of progressive muscular dystrophy in children: a systematic review and meta-analysis.

ABSTRACT:

Background

Hormonal drug therapy has been widely used in clinical practice for the treatment of progressive muscular dystrophy (PMD). Glucocorticoids, as a common drug in the clinical treatment of PMD, have been reported in several clinical studies.

Methods

Chinese and English databases were respectively searched using "randomized controlled trials", "Duchenne-type myotonic dystrophy", "glucocorticoids", Prednisone", "Prednisolone", and "Methylprednisolone", and "Defibrotide" were used as search terms. The meta-analysis was performed using the RevMan 5.3 and Stata 13 software provided by the Cochrane system.

Results

this study included five randomized controlled trials, all of which described the correct randomization method. There were four detailed descriptions of h

SUBMITTER: Ru L 

PROVIDER: S-EPMC8649594 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature