Auditory Dysfunction Among Individuals With Neurofibromatosis Type 1.

ABSTRACT:

Importance

Neurofibromatosis type 1 (NF1) affects hearing through disruption of central auditory processing. The mechanisms, functional severity, and management implications are unclear.

Objective

To investigate auditory neural dysfunction and its perceptual consequences in individuals with NF1.

Design, setting, and participants

This case-control study included children and adults with NF1 and control participants matched on age, sex, and hearing level. Patients were recruited through specialist neurofibromatosis and neurogenetic outpatient clinics between April and September 2019. An evaluation of auditory neural activity, monaural/binaural processing, and functional hearing was conducted. Diffusion-weighted magnetic resonance imaging (MRI) data were collected from a

SUBMITTER: Rance G 

PROVIDER: S-EPMC8649832 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature