Efficacy and Safety Associated With Immune Checkpoint Inhibitors in Unresectable Hepatocellular Carcinoma: A Meta-analysis.

ABSTRACT:

Importance

Immune checkpoint inhibitors (ICIs) have yielded conflicting results in hepatocellular carcinoma (HCC). The overall effect of ICIs compared with standard therapies in unresectable HCC requires more research.

Objective

To estimate the efficacy and safety associated with ICIs compared with standard therapies in patients with unresectable HCC.

Data sources

PubMed, Cochrane Library, Web of Science, Latin American and Caribbean Health Sciences Literature, and American Society of Clinical Oncology and European Society of Medical Oncology meeting proceedings were systematically searched. Reference lists from studies selected by electronic searching were manually searched to identify additional relevant studies. The search included literature published or presented

SUBMITTER: Jacome AA 

PROVIDER: S-EPMC8649834 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature