Magnetic resonance imaging detected radiation-induced changes in patients with proton radiation-treated arteriovenous malformations.

ABSTRACT:

Background

Treatment of intracranial arteriovenous malformations (AVMs) includes surgery, radiation therapy, endovascular occlusion, or a combination. Proton radiation therapy enables very focused radiation, minimizing dose to the surrounding brain.

Purpose

To evaluate the presence of radiation-induced changes on post-treatment MRI in patients with AVMs treated with proton radiation and to compare these with development of symptoms and nidus obliteration.

Material and methods

Retrospective review of pre- and post-treatment digital subtraction angiography and MRI and medical records in 30 patients with AVMs treated with proton radiation. Patients were treated with two or five fractions; total radiation dose was 20-35 physical Gy. Vasogenic edema (minimal, perinidal, or

SUBMITTER: Correia de Verdier M 

PROVIDER: S-EPMC8649916 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature