Applicability of several rooted phylogenetic network algorithms for representing the evolutionary history of SARS-CoV-2.

ABSTRACT:

Background

Rooted phylogenetic networks are used to display complex evolutionary history involving so-called reticulation events, such as genetic recombination. Various methods have been developed to construct such networks, using for example a multiple sequence alignment or multiple phylogenetic trees as input data. Coronaviruses are known to recombine frequently, but rooted phylogenetic networks have not yet been used extensively to describe their evolutionary history. Here, we created a workflow to compare the evolutionary history of SARS-CoV-2 with other SARS-like viruses using several rooted phylogenetic network inference algorithms. This workflow includes filtering noise from sets of phylogenetic trees by contracting edges based on branch length and bootstrap support, followe

SUBMITTER: Wallin R 

PROVIDER: S-EPMC8649988 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature