NHC-CDI Betaine Adducts and Their Cationic Derivatives as Catalyst Precursors for Dichloromethane Valorization.

ABSTRACT: Zwitterionic adducts of N-heterocyclic carbene and carbodiimide (NHC-CDI) are an emerging class of organic compounds with promising properties for applications in various fields. Herein, we report the use of the ICyCDI(p-Tol) betaine adduct (1a) and its cationic derivatives 2a and 3a as catalyst precursors for the dichloromethane valorization via transformation into high added value products CH₂Z₂ (Z = OR, SR or NR₂). This process implies selective chloride substitution of dichloromethane by a range of nucleophiles Na⁺Z^- (preformed or generated in situ from HZ and an inorganic base) to yield formaldehyde-derived acetals, dithioacetals, or aminals with full selectivity. The reactions are conducted in a

SUBMITTER: Sanchez-Roa D 

PROVIDER: S-EPMC8650018 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature