On-Chip Cyclic Voltammetry Measurements Using a Compact 1024-Electrode CMOS IC.

ABSTRACT: Complementary metal-oxide-semiconductor (CMOS) microelectrode arrays integrate amplifier arrays with on-chip electrodes, offering high-throughput platforms for electrochemical sensing with high spatial and temporal resolution. Such devices have been developed for highly parallel constant voltage amperometric detection of transmitter release from multiple cells with single-vesicle resolution. Cyclic voltammetry (CV) is an electrochemical method that applies voltage waveforms, which provides additional information about electrode properties and about the nature of analytes. A 16-channel, 64-electrode-per-channel CMOS integrated circuit (IC) fabricated in a 0.5 μm CMOS process for CV is demonstrated. Each detector consists of only 11 transistors and an integration capacitor with a unit dimens

SUBMITTER: Huang M 

PROVIDER: S-EPMC8650766 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature