Cognitive outcomes in late childhood and adolescence of neonatal hypoxic-ischemic encephalopathy.

ABSTRACT: Hypoxic-ischemic encephalopathy (HIE) is the most common cause of neonatal encephalopathy with a global incidence of approximately 1 to 8 per 1,000 live births. Neonatal encephalopathy can cause neurodevelopmental and cognitive impairments in survivors of hypoxic-ischemic insults with and without functional motor deficits. Normal neurodevelopmental outcomes in early childhood do not preclude cognitive and behavioral difficulties in late childhood and adolescence because cognitive functions are not yet fully developed at this early age. Therapeutic hypothermia has been shown to significantly reduced death and severe disabilities in term newborns with HIE. However, children treated with hypothermia therapy remain at risk for cognitive impairments and follow-up is necessary throughout late ch

SUBMITTER: Lee BL 

PROVIDER: S-EPMC8650814 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature