Pertussis immunisation in infancy and atopic outcomes: A protocol for a population-based cohort study using linked administrative data.

ABSTRACT:

Introduction

The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. Findings from a case-control study suggest that compared to immunisation with acellular pertussis vaccine, early priming of infants with whole-cell pertussis vaccine may be associated with a lower risk of subsequent IgE-mediated food allergy. If whole-cell vaccination is protective of food allergy and other atopic diseases, especially if protective against childhood asthma, the population-level effects could justify its preferential recommendation. However, the potential beneficial effects of whole-cell pertussis vaccination fo

SUBMITTER: Perez Chacon G 

PROVIDER: S-EPMC8651097 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature