Associations between obesity, metabolic health, and the risk of breast cancer in East Asian women.

ABSTRACT:

Background

This study examined the associations between metabolic syndrome(MetS), obesity, their combination as a metabolic obesity phenotype, and the risk of breast cancer in East Asian postmenopausal women.

Methods

A total of 3,095,336 postmenopausal cancer-free women aged 40-79 years who underwent the National Health Insurance Service health examination between 2009 and 2010 were included. The incidence of invasive breast cancer was followed up until 2018. The presence of obesity (body mass index[BMI] ≥25 kg/m²), MetS, and each component of MetS was investigated.

Results

Obesity and MetS were associated with breast cancer risk, but when the effects of obesity and MetS were mutually adjusted, the associations were attenuated, especially for MetS. Only ele

SUBMITTER: Park B 

PROVIDER: S-EPMC8651731 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature