The Additive Effect of Platelet-Rich Plasma in the Treatment of Actively Bleeding Peptic Ulcer.

ABSTRACT:

Background/aims

Peptic ulcer bleeding is the most common cause of upper gastrointestinal tract bleeding. Platelet-rich plasma (PRP) enhances tissue repair, and is therefore used in various medical treatments. A combination of mechanical or electrothermal hemostasis has been recommended for upper gastrointestinal tract bleeding treatment. This study evaluated the additive efficacy of PRP in bleeding peptic ulcer hemostasis and recovery.

Methods

Eighty patients with peptic ulcer bleeding were initially treated by hemoclipping, and were randomly chosen for either additional PRP (n=40) or additional epinephrine (n=40) injections. Both groups were compared with regard to achieving hemostasis and the frequency of complications.

Results

Hemostasis was immediately achieved in

SUBMITTER: Seleem WM 

PROVIDER: S-EPMC8652155 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature