Risk Factors and Brain Metabolic Mechanism of Sleep Disorders in Autoimmune Encephalitis.

ABSTRACT:

Background

Sleep disorders (SDs) in autoimmune encephalitis (AE) have received little attention and are poorly understood. We investigated the clinical characteristics, risk factors, and cerebral metabolic mechanism of SD in AE.

Methods

Clinical, laboratory, and imaging data were retrospectively reviewed in 121 consecutively patients with definite AE. The risk factors for SD in AE were estimated by logistic regression analysis. Group comparisons based on ¹⁸F-fluorodeoxy-glucose positron emission tomography (¹⁸F-FDG-PET) data were made between patients with and without SD, to further analyze potential brain metabolic mechanism of SD in AE.

Results

A total of 52.9% patients (64/121) with SD were identified. The multivariate logistic model analysis

SUBMITTER: Liu X 

PROVIDER: S-EPMC8652207 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature