SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study.

ABSTRACT:

Objective

The primary aim of this article was to describe SARS-CoV-2 infection among pregnant women during the wild-type and Alpha-variant periods in Italy. The secondary aim was to compare the impact of the virus variants on the severity of maternal and perinatal outcomes.

Design

National population-based prospective cohort study.

Setting

A total of 315 Italian maternity hospitals.

Sample

A cohort of 3306 women with SARS-CoV-2 infection confirmed within 7 days of hospital admission.

Methods

Cases were prospectively reported by trained clinicians for each participating maternity unit. Data were described by univariate and multivariate analyses.

Main outcome measures

COVID-19 pneumonia, ventilatory support, intensive care unit (ICU) admission, mode

SUBMITTER: Donati S 

PROVIDER: S-EPMC8652503 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature