Repurposing an Antiviral Drug against SARS-CoV-2 Main Protease.

ABSTRACT: This article highlights recent pioneering work by Günther et al. towards the discovery of potential repurposed antiviral compounds (peptidomimetic and non-peptidic) against the SARS-CoV-2 main protease (M^pro ). The antiviral activity of the most potent drugs is discussed along with their binding mode to M^pro as observed through X-ray crystallographic screening.

SUBMITTER: Sarkar A 

PROVIDER: S-EPMC8652770 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature