The long-term effects of lower versus higher oxygenation levels in adult ICU patients - protocol for a systematic review.

ABSTRACT:

Background

Many organs can remain impaired after discharge from the intensive care unit (ICU) leading to temporal or permanent dysfunctions. Long-term impairments may be affected by supplemental oxygen, a common treatment in ICU, having both potential beneficial and harmful long-lasting effects. This systematic review aims to assess the long-term outcomes of lower versus higher oxygen supplementation and/or oxygenation levels in adults admitted to ICU.

Methods

We will include trials differentiating between a lower and a higher oxygen supplementation or a lower and a higher oxygenation strategy in adults admitted to the ICU. We will search major electronic databases and trial registers for randomised clinical trials. Two authors will independently screen and select references

SUBMITTER: Crescioli E 

PROVIDER: S-EPMC8652878 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature