Association of bilateral salpingo-oophorectomy with all cause and cause specific mortality: population based cohort study.

ABSTRACT:

Objectives

To determine if bilateral salpingo-oophorectomy, compared with ovarian conservation, is associated with all cause or cause specific death in women undergoing hysterectomy for non-malignant disease, and to determine how this association varies with age at surgery.

Design

Population based cohort study.

Setting

Ontario, Canada from 1 January 1996 to 31 December 2015, and follow-up to 31 December 2017.

Participants

200 549 women (aged 30-70 years) undergoing non-malignant hysterectomy, stratified into premenopausal (<45 years), menopausal transition (45-49 years), early menopausal (50-54 years), and late menopausal (≥55 years) groups according to age at surgery; median follow-up was 12 years (interquartile range 7-17).

Exposures

Bilateral salpingo

SUBMITTER: Cusimano MC 

PROVIDER: S-EPMC8653240 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature