Comparison of COVID-19 studies registered in the clinical trial platforms: A research ethics analysis perspective.

ABSTRACT:

Background

The coronavirus disease (COVID-19) treatment must be based on scientific methods such as clinical trials. Trials involving human subjects and those requiring a risk-benefit analysis may occasionally face challenges owing to the time limitations in the pandemic.

Methodology

This study analyses the WHO's International Clinical Trials Registry Platform and clinicaltrials.gov, where most COVID-19 clinical trials are registered, according to ethical criteria including study design, conflicts of interest, enrollment of healthcare workers, study locations, site-, design-, and participant-related issues. The discussion is based on three aspects: the quality of the information to be produced, the relevance to significant health problems, and the creation or evaluation of i

SUBMITTER: Buruk B 

PROVIDER: S-EPMC8653301 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature