Sociodemographic and lifestyle factors associated with the neutrophil-to-lymphocyte ratio.

ABSTRACT:

Purpose

The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation with established prognostic value in patients with cancer. Although high NLR is associated with poorer clinical outcomes, factors that influence the magnitude of NLR independently of disease are poorly understood.

Methods

We identified 48,023 adults who participated in the National Health and Nutrition Examination Survey (1999-2016). Demographic, socioeconomic, and lifestyle factors associated with the magnitude of NLR after adjusting for comorbidities including heart disease, cancer, diabetes, and hypertension, and medications including aspirin, were identified. Effect modification by comorbidity status and demographics was explored.

Results

Female gender, age less than 60 years, an

SUBMITTER: Howard R 

PROVIDER: S-EPMC8653546 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature