Development of a radiographic scoring system for new bone formation in gout.

ABSTRACT:

Background

Features of new bone formation (NBF) are common in tophaceous gout. The aim of this project was to develop a plain radiographic scoring system for NBF in gout.

Methods

Informed by a literature review, scoring systems were tested in 80 individual 1st and 5th metatarsophalangeal joints. Plain radiography scores were compared with computed tomography (CT) measurements of the same joints. The best-performing scoring system was then tested in paired sets of hand and foot radiographs obtained over 2 years from an additional 25 patients. Inter-reader reproducibility was assessed using intraclass correlation coefficients (ICC). NBF scores were correlated with plain radiographic erosion scores (using the gout-modified Sharp-van der Heijde system).

Results

Following

SUBMITTER: Son CN 

PROVIDER: S-EPMC8653557 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature