Prevalence and Clinical Features of Sessile Serrated Polyps: A Systematic Review.

ABSTRACT:

Background & aims

Sessile serrated polyps (SSPs) could account for a substantial proportion of colorectal cancers. We aimed to increase clarity on SSP prevalence and clinical features.

Methods

We performed a systematic review of MEDLINE, Web of Science, Embase, and Cochrane databases for original studies published in English since 2000. We included studies of different populations (United States general or similar), interventions (colonoscopy, autopsy), comparisons (world regions, alternative polyp definitions, adenoma), outcomes (prevalence, clinical features), and study designs (cross-sectional). Random-effects regression was used for meta-analysis where possible.

Results

We identified 74 relevant colonoscopy studies. SSP prevalence varied by world region, from 2.6%

SUBMITTER: Meester RGS 

PROVIDER: S-EPMC8653879 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature