Second-sphere effects on H₂O₂ activation by non-heme Fe^II complexes: role of a phenol group in the [H₂O₂]-dependent accumulation of Fe^IVO vs. Fe^IIIOOH.

ABSTRACT: Redox metalloenzymes achieve very selective oxidation reactions under mild conditions using O₂ or H₂O₂ as oxidants and release harmless side-products like water. Their oxidation selectivity is intrinsically linked to the control of the oxidizing species generated during the catalytic cycle. To do so, a second coordination sphere is used in order to create a pull effect during the activation of O₂ or H₂O₂, thus ensuring a heterolytic O-O bond cleavage. Herein, we report the synthesis and study of a new non-heme Fe^II complex bearing a pentaazadentate first coordination sphere and a pendant phenol group. Its reaction with H₂O₂ generates the classical Fe^IIIOOH species at high H_2</

SUBMITTER: Rebilly JN 

PROVIDER: S-EPMC8653992 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature