Twenty-Four-Hour Central (Aortic) Systolic Blood Pressure: Reference Values and Dipping Patterns in Untreated Individuals.

ABSTRACT: Central (aortic) systolic blood pressure (cSBP) is the pressure seen by the heart, the brain, and the kidneys. If properly measured, cSBP is closer associated with hypertension-mediated organ damage and prognosis, as compared with brachial SBP (bSBP). We investigated 24-hour profiles of bSBP and cSBP, measured simultaneously using Mobilograph devices, in 2423 untreated adults (1275 women; age, 18-94 years), free from overt cardiovascular disease, aiming to develop reference values and to analyze daytime-nighttime variability. Central SBP was assessed, using brachial waveforms, calibrated with mean arterial pressure (MAP)/diastolic BP (cSBP_MAP/DBPcal), or bSBP/diastolic blood pressure (cSBP_SBP/DBPcal), and a validated transfer function, resulting in 144 509 valid brach

SUBMITTER: Weber T 

PROVIDER: S-EPMC8654125 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature